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KMID : 0372919880090010067
Journal of Biomedical Engineering Research
1988 Volume.9 No. 1 p.67 ~ p.71
Synthesis of Poly (hydroxypropyl methacrylate-co-N- vinylpyrrolidone) hydrogel and its Application to the Contact Lens



Abstract
Poly (HPMA/NVP) hydrogel was synthesized according to the composition and the con- centration of the crosslinking agent. The swelling degree of the P(HPMA/NVP) hydrogel decreased with increasing of P(HPMA) composition and crosslinking agent. The glass transi- tion and softening temperatures of the P(HPMA/NVP) increased with increasing of P(HPMA) composition. The composition of P(HPMA/NVP) : 70/30 and the concentration of the crosslin- king agent of 0.5 wt % gave the optimum condition in the application to the contact lens. There were also adequate in the mechanical, refractive properties and in vivo test in the P(HPMA/ NVP): 70/30 system.
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